Szerző: admin | szept 28, 2023 | Blog
Singlera technologies 2: Early detection of residual molecular disease in colorectal cancer through circulating tumor DNA methylation Colorectal cancer (CRC), the second most common cause of cancer-related death, has a 5-year survival rate as low as 60%. This is...
Szerző: admin | aug 24, 2023 | Blog
Singlera technologies 1: Methylation haplotyping Identification of methylation haplotype blocks aids in the deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA. – Guo et al. Highlights Methylation haplotyping is a promising...
Szerző: admin | júl 26, 2023 | Blog
Targeting homologous recombination deficiency in ovarian cancer Maintaining genomic integrity and preventing cell death requires a complex network of molecular repair pathways, as DNA damage is a constantly occurring event (Frey et al., 2017). Homologous recombination...
Szerző: admin | jún 29, 2023 | Blog
Circulating endothelial cells in cancer Vascularization, a hallmark of tumorigenesis, is classically thought to occur exclusively through angiogenesis. However, there is a growing body of evidence that endothelial progenitor cells and proangiogenic hematopoietic cells...
Szerző: admin | máj 26, 2023 | Blog
Liquid biopsy in HPV-associated cervical cancer Cervical cancer and HPV Cervical cancer is one of the most frequently diagnosed cancer types in women worldwide. According to 2020 statistics, it is the fourth leading cause of cancer death [1], which is mainly due to...
Szerző: admin | febr 8, 2023 | Blog
Single-Cell Multi-omics of Circulating Tumor Cells As oncology analytical approaches are continuously developing, cancer can be understood in deeper and more detailed ways. However, we still struggle to capture potentially important subpopulations of tumor cells and...
