Szerző: admin | nov 30, 2023 | Blog
Singlera Technologies 4: Catching Pancreatic Cancer early with intricate methylation markers Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA. – Wu et al. Highlights One significant hurdle in...
Szerző: admin | okt 31, 2023 | Blog
Singlera technologies 3: Methylation signatures for hepatocellular carcinoma detection Identification of DNA methylation signatures for hepatocellular carcinoma detection and microvascular invasion prediction. – Hao et al. Highlights Hepatocellular carcinoma (HCC) is...
Szerző: admin | szept 28, 2023 | Blog
Singlera technologies 2: Early detection of residual molecular disease in colorectal cancer through circulating tumor DNA methylation Colorectal cancer (CRC), the second most common cause of cancer-related death, has a 5-year survival rate as low as 60%. This is...
Szerző: admin | aug 24, 2023 | Blog
Singlera technologies 1: Methylation haplotyping Identification of methylation haplotype blocks aids in the deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA. – Guo et al. Highlights Methylation haplotyping is a promising...
Szerző: admin | júl 26, 2023 | Blog
Targeting homologous recombination deficiency in ovarian cancer Maintaining genomic integrity and preventing cell death requires a complex network of molecular repair pathways, as DNA damage is a constantly occurring event (Frey et al., 2017). Homologous recombination...
Szerző: admin | jún 29, 2023 | Blog
Circulating endothelial cells in cancer Vascularization, a hallmark of tumorigenesis, is classically thought to occur exclusively through angiogenesis. However, there is a growing body of evidence that endothelial progenitor cells and proangiogenic hematopoietic cells...
