Singlera technologies 1: Methylation haplotyping

Singlera technologies 1: Methylation haplotyping

Singlera technologies 1: Methylation haplotyping Identification of methylation haplotype blocks aids in the deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA. – Guo et al. Highlights Methylation haplotyping is a promising...
Targeting homologous recombination deficiency in ovarian cancer

Targeting homologous recombination deficiency in ovarian cancer

Targeting homologous recombination deficiency in ovarian cancer Maintaining genomic integrity and preventing cell death requires a complex network of molecular repair pathways, as DNA damage is a constantly occurring event (Frey et al., 2017). Homologous recombination...
Circulating endothelial cells in cancer

Circulating endothelial cells in cancer

Circulating endothelial cells in cancer Vascularization, a hallmark of tumorigenesis, is classically thought to occur exclusively through angiogenesis. However, there is a growing body of evidence that endothelial progenitor cells and proangiogenic hematopoietic cells...