TECHNOLOGY
Liquid biopsy
Revolutionary non-invasive technology which opens new possibilities in cancer diagnostics and research.
CD PRIME™ for CTC analysis performs easy and automated protocol of CTC enrichment. This fully automated system enriches CTCs from untreated blood samples based on physical characteristics (Cell size and elasticity). In the CD-PRIME™ system, the whole blood sample is injected into the inlet of the loading chamber, and target CTCs are trapped on a membrane while the microfluidic disc rotates.
Liquid biopsy is a non-invasive examination method without involving the conventional invasive technique to observe cancer occurrence and metastasis by analyzing circulating cancer cells and cancer DNA in the blood.
It is possible to obtain a companion diagnosis and early cancer diagnosis using a blood sample without an invasive tissue biopsy.
Clinomics makes it possible to diagnose cancer earlier and more precisely, along with much more convenient treatment monitoring. Instead of more conventional and less accurate cancer detection by protein markers, which delay timely action to fight back against cancer, our Lab-on-a-Disc platform for liquid biopsy, CD-PRIME™ can provide much more accurate and abundant information by providing ctDNA (circulating tumor DNA) and CTC (circulating tumor cell) simultaneously to enhance the quality of cancer analysis.
It is common to find a few to thousands of CTCs in a single mL of blood sample of a cancer patient. However compared to billions of red blood cells, CTCs are very rare in blood samples. Enrichment of CTSs can be achieved effectively by the help of advanced microfluidics technology.
NGS
Next-generation sequencing (NGS) is a technology for determining the sequence of DNA or RNA to study genetic variation associated with diseases or other biological phenomena in entire genomes or targeted regions.
NGS technology fundamentally changes the kinds of questions doctors can ask and answer. Innovative sample preparation and data analysis enables to develop the precision diagnosis. With the help of this technology, whole genomes or target regions can be sequenced rapidly. We are capable of identifying rare tumors, mutations, and different pathogens, profiling gene expression, counting chromosomes, detecting epigenetic changes, or studying the human microbiome.
The diseases can be diagnosed accurately by analyzing a wide range of different samples. Thus, the service provides precise health information.
Precision medicine
Genetic analysis of tumors using Next-Generation Sequencing (NGS) provides the most specific treatment and medication for individualized patient care.
Clinomics is a leading company for early diagnosis of cancer/diseases based on genome and pursues to overcome aging and diseases through liquid biopsy and Multi-Omics technology. Clinomics specializes in offering a genome-based, early cancer diagnostic service through the technology of Multi-Omics analysis and simultaneous detection of CTC and cfDNA in the blood with our internationally renowned biomedical information processing abilities. Furthermore, Clinomics is a biotechnology company with leading technology for genome editing based on our unrivaled genomic technology.
We offer various solutions for customized precision medicine as a precision medicine company leading in personalized medicine, based on core values of challenge, innovation, integrity, and communication. We are releasing a variety of products through consistent research and development.
COVID-19 testing solutions
LAMP – Loop-mediated isothermal amplification
LAMP was developed by Notomi et al. (2000) as a simple and rapid gene amplification technique. LAMP provides high specificity and selectivity by using 4 primers recognizing 6 distinct regions on the target sequences. The process can be completed quickly due to the high amplification efficiency under isothermal conditions without the need of expensive thermal cycle PCR machines. Amplification can be visualized in the tubes due to the presence of fluorescent dyes.
Type
Molecular Test
Standart test
Rapid test
Intended use
Molecular Test
Standart test
Rapid test
Sample
Molecular Test
Standart test
Rapid test
Target
Molecular Test
Standart test
Rapid test
Limit of Detection (LoD)
Molecular Test
Standart test
Rapid test
RNA extraction time
Molecular Test
Standart test
Rapid test
Turn around time
Molecular Test
Standart test
Rapid test
Total time
Molecular Test
Standart test
Rapid test
Reagent storage temp.
Molecular Test
Standart test
Rapid test
Optical detection
Molecular Test
Standart test
Rapid test
Detection chemistry
Molecular Test
Standart test
Rapid test
While the standard diagnostic methods with gene amplification provide highly accurate results, it takes 2 to 3 hours to complete testing. Rapid antigen tests are faster due to gene amplification elimination, but cannot diagnose low viral load samples or samples from early stage patients. 1copy™ COVID-19 MDx Kit Professional is a novel molecular-based COVID-19 diagnostic platform that offers high accuracy and speed.
Smart, Fast, Reliable
1copy™ COVID-19 MDx Kit Professional is a portable and compact device with the power of lab-quality molecular testing that can be used in hospitals, schools, logistics centers, and many other crowded places.
In particular, health professionals are doing their best to care for both symptomatic and asymptomatic patients in this era of the COVID-19 pandemic. 1copy™ COVID-19 MDx Kit Professional offers convenience with an easy-to-use process and makes it possible for frequent testing.
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